5750-76-5, A common compound: 5750-76-5, name is 2,4,5-Trichloropyrimidine,molecular formula is C4HCl3N2, it can change the direction of chemical reaction, and react with certain compounds to generate new functional products. A new synthetic method of this compound is introduced below.
Take 3 (23.44 mmol) and DIPEA (4.5 g, 35.16 mmol)2,4-Dichloro-5-R-pyrimidine (3.8 g, 23.44 mmol) was slowly added to 50 mL of 1,4-dioxane.After heating at 60 C for 2 hours,The reaction is complete, cooling,Add 400 mL of water, precipitate a yellow-white solid, suction filtration, and dry to give a white solid.The next reaction was not directly purified.
With the rapid development of chemical substances, we look forward to future research findings about 5750-76-5.
Reference:
Patent; Dalian Medical University Affiliated The First Hospital; Dalian Medical University; Yuan Hong; Li Si; Zhao Jingyuan; Wu Xiangdong; Wang Xiaoxi; Wang Nan; Yao Bingjie; Zhao Dan; Yao Yao; Sun Xiuli; Ma Xiaodong; (23 pag.)CN108610295; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia