The origin of a common compound about 6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2434-53-9, name is 6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione. This compound has unique chemical properties. The synthetic route is as follows. Safety of 6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione

Mixture of 6-amino-1-methyl-pyrimidine -2,4 (1H, 3H) – dione(5.46g, 40.0mmol) and bromo succinimide (7.56g, 42.0mmol) in acetonitrile (100 mL) solution was heated to reflux under nitrogen protection for 1.5 hours. The reaction was cooled to room temperature, filtered, (20 mL) and washed to remove the solvent, the resulting solid was washed with water, and dried to give 6-amino-5-bromo-1-methyl-pyrimidine -2,4 (1H, 3H)-dione (8.6g, white solid), yield: 98%

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 2434-53-9, 6-Amino-1-methylpyrimidine-2,4(1H,3H)-dione.

Reference:
Patent; Sichuan Gooddoctor Pharmaceutical Group Co., Ltd.; Wu, Lingyun; Zhang, Peng; Zhang, Li; Li, Jian; Chen, Shuhui; Geng, Funeng; Chen, Yongmei; Liu, Bin; Ma, Xiuying; (109 pag.)CN105566324; (2016); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia