The origin of a common compound about 611-08-5

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611-08-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 611-08-5, name is 5-Nitrouracil. This compound has unique chemical properties. The synthetic route is as follows.

5-nitrouracil (10.00 g, 64 mmole) and potassium carbonate were stirred in dimethylformamide (50 ML) for 15 min.. A solid formed.. iodomethane (5.3 ML, 85 mmol) was added and the flask was shaken until the solid dissolved.. After the reaction mixture was stirred for 30 min., 2% NaOH (w/v) (200 ML) was added, followed by water (100 ML).. The solution was washed with ethyl acetate (100 ML), and the aqueous layer was acidified to PH 3 with 1.0N HCl. A precipitate formed as the PH was lowered.. After allowing the heterogeneous solution to stand for 16 hours, the product was filtered, washed with water, and air dried.. The title compound was isolated in 77% yield as a yellow powder; m.p. 249 to 250 C.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 611-08-5, 5-Nitrouracil.

Reference:
Patent; Corvas International, Inc.; US6342504; (2002); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia