Application of 14080-50-3 ,Some common heterocyclic compound, 14080-50-3, molecular formula is C6H4N2OS, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
2nd step: 250 ml single-port bottle adding CP0763A 45g, phosphorus oxychloride 75 ml and N, N – dimethyl aniline 7.5 ml, heating reflux 2 hours for inspection, raw material of reaction. After the steaming and remove most of the phosphorus oxychloride, adding ice water quenching. Then the pH is adjusted with ammonia water 6 – 7, filtering, the filter cake is washed for three times. Solid dissolves clear EA adding activated carbon to decolorize. Drying reciprocation product job (CP0763 B) 34g. Yield: 68%;
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,14080-50-3, its application will become more common.
Reference:
Patent; Yang, Wei; Niu, Yuqiang; (14 pag.)CN104725398; (2017); B;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia