Ungoren, Sevket Hakan published the artcileDBU-catalyzed, aromatization-oriented, regioselective domino synthesis of 2-aminopyrimidines from β-dicarbonyl compounds, DMF-DMA, and cyanamide, SDS of cas: 66373-25-9, the main research area is dicarbonyl preparation cyanamide DMF dimethylacetal DBU tandem multicomponent cyclocondensation; aminopyrimidine preparation regioselective; -Dicarbonyl compound; 2-Aminopyrimidine; Cyanamide; DBU; Domino synthesis; Four-component; MCR.
A multicomponent domino synthesis was developed for the preparation of 2-aminopyrimidines from β-dicarbonyl compounds, N,N-dimethylformamide di-Me acetal and cyanamide. The protocol was used for the regioselective preparation of 4-amide/ester/ketone substituted 2-aminopyrimidines. Twelve 2-aminopyrimidines were isolated in good yields (56-93%).
Molecular Diversity published new progress about Aromatic heterocyclic amines Role: SPN (Synthetic Preparation), PREP (Preparation). 66373-25-9 belongs to class pyrimidines, name is 1-(2-Amino-4-methylpyrimidin-5-yl)ethanone, and the molecular formula is C7H9N3O, SDS of cas: 66373-25-9.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia