Varga, Laszlo et al. published their research in Tetrahedron in 2003 | CAS: 40230-24-8

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Application In Synthesis of 4,6-Diphenylpyrimidin-2-amine

Solution-phase parallel synthesis of 4,6-diaryl-pyrimidine-2-ylamines and 2-amino-5,5-disubstituted-3,5-dihydro-imidazol-4-ones via a rearrangement was written by Varga, Laszlo;Nagy, Tamas;Kovesdi, Istvan;Benet-Buchholz, Jordi;Dorman, Gyorgy;Urge, Laszlo;Darvas, Ferenc. And the article was included in Tetrahedron in 2003.Application In Synthesis of 4,6-Diphenylpyrimidin-2-amine This article mentions the following:

The reaction of chalcones R1COCH:CHR2 [R1, R2 = Ph, 2-furyl, 2-thienyl, 4-FC6H4; R1 = Ph, R2 = 2-MeOC6H4, 4-MeOC6H4, 3,4-(MeO)2C6H3; etc.] with guanidine was investigated in the presence of H2O2 as an oxidizing agent. Depending on the order of the addition, either 4,6-diarylpyrimidin-2-ylamine I or 2-amino-5,5-disubstituted-3,5-dihydroimidazol-4-one II was obtained. The structures of the imidazolinones II (R1 = R2 = Ph) and III were elucidated by NMR spectroscopy and X-ray crystallog. and a mechanism of its formation was proposed. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8Application In Synthesis of 4,6-Diphenylpyrimidin-2-amine).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Application In Synthesis of 4,6-Diphenylpyrimidin-2-amine

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia