Pyrimidine is a nitrogenous base similar to benzene (a six-membered ring) and includes cytosine, thymine, and uracil as bases used for DNA or RNA. 4595-59-9, formula is C4H3BrN2, Name is 5-Bromopyrimidine. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Electric Literature of 4595-59-9.
Wang, Danfeng;Huang, Hai;Zhu, Xiaolin research published 《 Development of anthrazoline photocatalysts for promoting amination and amidation reactions》, the research content is summarized as follows. In this work, the optical and electrochem. properties of a series of organophotocatalysts each bearing an anthrazoline framework, was synthesized and determined as well as demonstrated their catalytic competencies in promoting C-N bond formation by leveraging photoredox catalysis. The chosen anthrazoline photocatalyst allowed for access to diverse amines and amides in good to excellent yields (up to 96%).
Electric Literature of 4595-59-9, 5-Bromopyrimidine is a reactive intermediate that is used in the synthesis of 4-methoxyphenylboronic acid. 5-Bromopyrimidine has been shown to be nucleophilic, reacting with β-amino acids under basic conditions to form the corresponding 2-bromo amide. It also undergoes cross-coupling reactions with halides and can be used as a building block for other organic compounds. 5-Bromopyrimidine has optical properties that are characteristic of aromatic molecules, including strong absorption bands in the ultraviolet region and visible light region.
5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine., 4595-59-9.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia