Suspect, non-target and target screening of pharmaceuticals and personal care products (PPCPs) in a drinking water system was written by Wang, Yu-Qing;Hu, Li-Xin;Zhao, Jia-Hui;Han, Yu;Liu, You-Sheng;Zhao, Jian-Liang;Yang, Bin;Ying, Guang-Guo. And the article was included in Science of the Total Environment in 2022.Electric Literature of C11H12N4O3S This article mentions the following:
Drinking water quality and safety are very important in protecting human health. Chem. contaminants in drinking water system have become an increasing concern. Our knowledge about what chems. are present in drinking water is still limited. Here we screened chems. of emerging concern in a conventional drinking water system based on suspect, non-target screening and target anal., and assessed their variations in different seasons and different treatment units. Overall, 720 chems. were identified with HRMS databases from the suspect and non-target screening and 48 chems. in five categories were further confirmed with the high confidence level, with predominance of pharmaceuticals and personal care products (PPCPs) and pesticides. Four compounds are newly found in aquatic environment with no literature or chem. occurrence data record. Temporal variations and variable removals were observed for these chems. in the system. Target anal. of 110 PPCPs showed detection of 21, 19 and 22 compounds in the drinking water treatment plant with a concentration range of 0.11-844 ng/L in the three seasons, but only 8, 9 and 15 compounds detected in tap water (0.16-32.5 ng/L). The variations of the detected chems. were less obvious in tap water, with most having concentrations below 2 ng/L. The results indicated efficient removal for most PPCPs in the drinking water system. The findings from this study demonstrated the strong capability of combined non-target screening and target anal. in identifying and assessing various organic chems. in drinking water system. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Electric Literature of C11H12N4O3S).
4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own.Electric Literature of C11H12N4O3S
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia