On November 5, 2014, Wang, Yuwan; Pan, Zhende; Dai, Xiaoxi; Ren, Yanan; Shen, Li published a patent.Formula: C17H24N4O6 The title of the patent was A preparation method of tulathromycin oily injection. And the patent contained the following:
The invention relates to a preparation method of tulathromycin oily injection with co-solvent, which is glycerol formal/benzyl benzoate/oily medium, wherein the oily medium comprises Et oleate, and iso-Pr myristate, and the formulation also includes hydrogenated castor oil and soy lecithin. The co-solvent can also prepare a compound preparation of tulathromycin and trimethoprim lactate. The preparation has good stability, good physiol. tolerance, and high drug loading coefficient, so that it is an animal-oriented oily injection both good in slow release and controlled release. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Formula: C17H24N4O6
The Article related to tulathromycin oily injection formulation cosolvent antioxidant, Pharmaceuticals: Formulation and Compounding and other aspects.Formula: C17H24N4O6
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia