Synthesis of new pyrimidine-4-carboxylic acid derivatives was written by Warczykowska, Iwona;Wojciechowski, Jan. And the article was included in Polish Journal of Chemistry in 1980.Formula: C5H2ClN3 This article mentions the following:
Aminolysis of 2-chloro-4-cyanopyridine (I) gave the nitriles II [R = cyano; R1 = H, R2 = 4-ClC6H4, 2-MeOC6H4, 4-Me2NC6H4; R1 = R2 = Et; R1R2 = (CH2CH2)2O] which were hydrolyzed with 5% aqueous NaOH to the acids II (R = CO2H). Treatment of I with NaOMe-MeOH gave the ester III which was hydrolyzed to the acid with aqueous NaOH. In the experiment, the researchers used many compounds, for example, 2-Chloropyrimidine-4-carbonitrile (cas: 75833-38-4Formula: C5H2ClN3).
2-Chloropyrimidine-4-carbonitrile (cas: 75833-38-4) belongs to pyrimidine derivatives. The pyrimidine nitrogenous bases are derived from the organic compound pyrimidine through the addition of various functional groups. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Formula: C5H2ClN3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia