Identification of indicator PPCPs in landfill leachates and livestock wastewaters using multi-residue analysis of 70 PPCPs: Analytical method development and application in Yangtze River Delta, China was written by Wu, Dongquan;Sui, Qian;Yu, Xia;Zhao, Wentao;Li, Qiang;Fatta-Kassinos, Despo;Lyu, Shuguang. And the article was included in Science of the Total Environment in 2021.COA of Formula: C11H12N4O3S This article mentions the following:
The source apportionment of pharmaceuticals and personal care products (PPCPs) in the water environment based on indicators (i-PPCPs) requires a comprehensive characterization of various emission sources using reliable anal. methods for a wide spectrum of PPCPs. In this study, a robust and sensitive method based on solid phase extraction (SPE) and ultra-high performance liquid chromatog. coupled with tandem mass spectrometry (UHPLC-MS/MS) for analyzing 70 PPCPs belonging to 17 therapeutic classes in landfill leachates and livestock wastewaters was developed. The SPE cartridges, sample pH, elution solvents and chelating agent additions were optimized, and acceptable recoveries (60- 130% for 67 target compounds), low method quantification limits (landfill leachate: 3- 1309 ng/L; livestock wastewater: 3- 686 ng/L) and high precisions (repeatability: 0- 20% for over 99% injections; reproducibility: 0- 20% for over 90% injections) were obtained. Using the optimized anal. method to characterize PPCPs in the typical landfill leachate and livestock wastewater in Yangtze River Delta, China, we found anthelmintics, which were first reported in landfill leachates globally, exhibited the highest concentration (albendazole, maximum concentration of 61.6娓璯/L), and therefore proposed albendazole as one of the promising i-PPCP candidates in landfill leachates. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3COA of Formula: C11H12N4O3S).
4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own.COA of Formula: C11H12N4O3S
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia