On April 13, 2021, Xie, Yanjun; Cao, Haifeng; Zhu, Yuandong; Zhu, Xuefeng; Cao, Yonghui; Liu, Guodong published a patent.Synthetic Route of 23256-42-0 The title of the patent was Preparation method of soluble florfenicol powder. And the patent contained the following:
The invention discloses a preparation method of soluble florfenicol powder. The soluble florfenicol powder is prepared from the following raw materials in parts by mas: 5-15 parts of florfenicol, 2-5 parts of beta-cyclodextrin, 3-7 parts of polyethylene glycol, 2-6 parts of silicon dioxide, 2-5 parts of acidic auxiliary materials and 2-3 parts of bactericidal ingredients. The florfenicol slow-release taste-masking preparation prepared by the process successfully solves the problem of poor palatability of florfenicol, masks the bitter taste of the medicine, increases the palatability, and greatly improves the appetite of animals; and according to the florfenicol slow-release taste-masking preparation, the drug florfenicol is successfully wrapped in the beta-cyclodextrin, so that the drug can be slowly released, the sustained-release effect is achieved, the drug action time is prolonged, the curative effect of the drug is improved, and the bioavailability is improved. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Synthetic Route of 23256-42-0
The Article related to florfenicol powder bioavailability sustained release formulation, Pharmaceuticals: Formulation and Compounding and other aspects.Synthetic Route of 23256-42-0
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia