Xu, Xu et al. published their research in Food Chemistry in 2022 | CAS: 1220-83-3

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Application of 1220-83-3

Application of silanized melamine sponges in matrix purification for rapid multi-residue analysis of veterinary drugs in eggs by UPLC-MS/MS was written by Xu, Xu;Zhao, Wenhao;Ji, Baocheng;Han, Yu;Xu, Gaigai;Jie, Mingsha;Wu, Nan;Wu, Yongmei;Li, Junguang;Li, Ke;Zhao, Dianbo;Bai, Yanhong. And the article was included in Food Chemistry in 2022.Application of 1220-83-3 This article mentions the following:

Fast and convenient matrix purification is an important prerequisite for high-throughput anal. of drug multiresidues in food. In this study, a silanized melamine sponge was prepared and first applied in the rapid determination of multiclass veterinary drugs in eggs by ultrahigh-performance liquid chromatog.-tandem mass spectrometry. Within five seconds, fast, convenient and efficient matrix separation could be achieved through simple soaking and squeezing. Compared to other matrix adsorbents, the developed material demonstrated equivalent or better purification performance. Good validation results were obtained in terms of drug recoveries (61.5%闂?7.0%, relative standard deviation (RSD) 闂?10.8%), and linearities (R2 闂?0.999), as well as low limits of quantitation (0.3 闂?10.9婵炴挾鎸撮悹铏规）g-1) and detection (0.1 闂?3.8婵炴挾鎸撮悹铏规）g-1). By analyzing 52 egg samples, high concentrations of ofloxacin, trimethoprim, metronidazole, and dimetridazole were found at 542.9, 121.2, 66.1 and 58.0婵炴挾鎸撮悹铏规）g-1, resp. The silanized melamine sponge has shown its great potential for rapid anal. of multiclass residues in food safety. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Application of 1220-83-3).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. A Cu-catalyzed and 4-HO-TEMPO-mediated [3 + 3] annulation of commercially available amidines with saturated ketones enables an efficient and facile synthesis of structurally important pyrimidines via a cascade reaction of oxidative dehydrogenation/annulation/oxidative aromatization.Application of 1220-83-3

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia