Pyrimidine is a nitrogenous base similar to benzene (a six-membered ring) and includes cytosine, thymine, and uracil as bases used for DNA or RNA. 4595-59-9, formula is C4H3BrN2, Name is 5-Bromopyrimidine. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Synthetic Route of 4595-59-9.
Yin, Nian;Chen, Haoyun;Yuan, Xingzhong;Zhang, Yi;Zhang, Mingjuan;Guo, Jiayin;Zhang, Yuanyuan;Qiao, Lu;Liu, Mengsi;Song, Kexin research published 《 Highly efficient photocatalytic degradation of norfloxacin via Bi2Sn2O7/PDIH Z-scheme heterojunction: Influence and mechanism》, the research content is summarized as follows. The severe pollution caused by antibiotics has prompted considerable concerns in recent decades. In this study, the Bi2Sn2O7/PDIH Z-scheme heterojunction photocatalyst was synthesized and highly photocatalytic activity on norfloxacin was obtained. The degradation of norfloxacin reached 98.71% in 90 min under visible light. The apparent rate constant of norfloxacin (0.4 903 min-1) was 3.65 and 20 times that of PDIH and the Bi2Sn2O7. Meanwhile, XPS, electrochem., Photoluminescence spectroscopy and ESR results showed that Z-scheme charge-transfer process facilitated the spatial carrier separation and preserve redox capability. Furthermore, the degradation intermediates of norfloxacin and their toxicities were evaluated. Finally, in the view of the survey about the impact of different water matrixes, it was found that the Bi2Sn2O7/PDIH maintained high efficiency in raw natural water. This work enriched inorganic/organic heterojunction engineering for PDIH, and provided the enormous potential for combining the Bi2Sn2O7 with PDIH to address the antibiotic pollution issues in the actual water treatment.
Synthetic Route of 4595-59-9, 5-Bromopyrimidine is a reactive intermediate that is used in the synthesis of 4-methoxyphenylboronic acid. 5-Bromopyrimidine has been shown to be nucleophilic, reacting with β-amino acids under basic conditions to form the corresponding 2-bromo amide. It also undergoes cross-coupling reactions with halides and can be used as a building block for other organic compounds. 5-Bromopyrimidine has optical properties that are characteristic of aromatic molecules, including strong absorption bands in the ultraviolet region and visible light region.
5-Bromopyrimidine undergoes direct metallation with lithuium diisopropylamide to yield 4-lithio-5-bromopyrimidine., 4595-59-9.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia