Zheng, Xing-xing; Ouyang, Wu-qing published an article in 2016, the title of the article was Preparation of erythromycin nanoemulsion and determination of its bacteriostatic activity in vitro.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate And the article contains the following content:
[Objective] To prepare erythromycin nanoemulsion, and to research its bacteriostatic activity in vitro. [Method] The preparation of the erythromycin nanoemulsion was optimized by studying the pseudoternary phase diagram. Broth dilution method was used to determine the MIC and MBC of erythromycin nanoemulsion on enteropathogenic Escherichia coli, Staphylococcus aureus, Pneumococcus and Proteus. [Result] The mass fraction of the components in erythromycin nanoemulsion included 2.8% erythromycin, 0.6% trimethoprim lactate, 35.2% EL-40, 7.5% cinnamaldehyde, and 53.9% distilled water. The susceptibility test revealed that the MIC of erythromycin nanoemulsion on enteropathogenic E. coli, S. aureus, Pneumococcus and proteus was 4, 1, 2 and 4μg/mL, resp. Their antibacterial effects significantly was better than other drugs. [Conclusion] The erythromycin nanoemulsion is successfully prepared, and its antibacterial effect in vitro is remarkable. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
The Article related to erythromycin nanoemulsion bacteriostatic, Pharmaceuticals: Formulation and Compounding and other aspects.Reference of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia